The aim of this study was to investigate the efficacy and tolerability of 15 mg meloxicam in comparison with 100 mg slow-release diclofenac in patients with osteoarthritis of the knee. Two hundred and fifty-eight patients were included in the intent-to-treat analysis; these were randomized into two groups to receive either 15 mg meloxicam (N 1.3% of people who took diclofenac (Voltaren, Zipsor, others) 1.2% of people who took Celebrex is less likely to cause serious side effects than naproxen. These side effects include heart Ratings & Reviews Diclofenac has an average rating of 7.4 out of 10 from a total of 687 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 20% reported a negative effect. Do not take more than 4 grams (from all sources) in 24 hours. When used in combination with opiates, it can decrease opiate requirements. Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Drugs: Aspirin, Ibuprofen, Naproxen, Meloxicam, Diclofenac, Flurbiprofen, Ketorolac; Rx Status: OTC and Rx Don't take acetaminophen if you drink more than a moderate amount of alcohol on a regular basis or if you have liver disease. NSAIDs such as aspirin, ibuprofen (Advil, Motrin), and naproxen (Aleve, Anaprox) may be more effective than acetaminophen for certain conditions because they reduce inflammation as well as relieve pain. But NSAID Naproxen. Doctors recommend a starting dose of 500 mg, then 250 mg every 6–8 hours as necessary. A person should not exceed a daily dose of 1,250 mg. This drug may impact heart, gastrointestinal Nabumetone was significantly more effective than naproxen for pain relief. More nabumetone treated patients withdrew due to lack of efficacy than naproxen treated patients. However, nabumetone was better tolerated than naproxen because fewer patients withdrew for adverse events or experienced severe adverse events, and significantly fewer Key takeaways: Meloxicam (Mobic) and celecoxib (Celebrex) are prescription-only medications that help relieve pain and inflammation. They’re commonly used to treat conditions like osteoarthritis and rheumatoid arthritis. Meloxicam and Celebrex work slightly differently in the body than other nonsteroidal anti-inflammatory drugs (NSAIDs). 27c3DU1.